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Wednesday, November 6, 2013

Gastric secretions

Which substances, other than backal point, atomic number 18 bring outd by the stomach? pick up their secreted and physiological roles. oTwo main cannular secretors are present in the stomach mucosa: Oxyntic/ stomachal glands pyloric glands In addition, mucus-secreting cells line the entire surface of the stomach (surface mucous glands). These secrete large quantities of a very pastelike mucus that coats the stomach mucosa with a gel layer of mucus, very much more than 1mm thick. These glands provide a major shell of surety for the stomach wall and contri exclusivelye to lubrication of food transport. The mucus produced by these mucus-secreting cells is alkaline (thus the normal stomach wall is not clear to the highly acidic and proteolytic stomach secretions directly).
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oOxyntic/gastric glands: Located on the inside surfaces of the body and fundus of the stomach pull in the proximal 80% of the stomach A typical gland is composed of 3 types of cells: mucous neck cells which secrete in general mucus; peptic/chief cells which secrete large quantities of pepsinogen; parietal/oxyntic cells which secrete hydrochloric acid (gastric acid) and intrinsic factor oPyloric glands: Are situated in the antral portion of the stomach Make up the distal 20% of the stomach resign mainly mucus for justification of the pyloric mucosa from gastric acid; similarly secrete the hormone gastrin and a mid master amount of pepsinogen oPepsinogen: Secreted mainly by peptic cells of the oxyntic glands, but a small amount is also secreted from the mucous cells of the oxyntic glands and from the pyloric glands (function is the! same) Molecular weight = c. 42,500 Da Is soundless when first secreted into the into the stomach Is activated to plaster cast pepsin: during this process, pepsinogen is bust into a 35,000 Da molecule (pepsin) HCl creates an acidic purlieu which allows pepsinogen to unfold and stick to itself in an autocatalytic fashion, thereby generating pepsin Pepsin acts as an...If you want to get a full essay, order it on our website: OrderCustomPaper.com

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